BIOcoretheorySem 3
BIOLOGICAL THERAPEUTICS
BIO 4407
Syllabus
- 01History of vaccine and immunotherapy development
- 02Antibody based therapeutics
- 03Chimeric antigen receptor engineering and clinical studies
- 04Introduction of molecular biology and history
- 05Oligonucleotide therapy (siRNA, miRNA, shRNA, antisense RNA)
- 06Development of gene transfer tools – viral and non-viral vectors
- 07Gene therapy for genetic diseases, infectious diseases
- 08Gene therapy clinical trials
- 09Basic concept of cancer treatment and immune response
- 10Cancer vaccines and preclinical studies
- 11Immune checkpoint regulation and cancer treatment
- 12Gene therapy for cancer
- 13Introduction to Stem Cells
- 14Stem cell-based therapies
- 15Ethical considerations
References
- Friedman T. 1999. The Development of Human Gene Therapy. Cold Spring Harbor, NY: Cold Spring Harbor Lab. Press.
- Knipe DM, Howley PM, eds. 2001. Fields Virology. Philadelphia, PA: Lippincott Williams & Wilkins.
- Hackett NR, Crystal RG. 2000. Adenovirus vectors for gene therapy. In Gene Therapy, ed. NS Templeton, DD Lasic, pp.17-39. New York: Marcel Dekker
- Lanza, R., Gearhart, J., Hogan, B., Melton, D., Pedersen, R., Thomas, E.D. and Thomson, J.A. eds., 2005. Essentials of stem cell biology. Elsevier.
- Owen, J.A., Punt, J., and Stranford, S.A., 2013. Kuby immunology p. 574. New York, NY, USA:: WH Freeman.
Credits Structure
3Lecture
0Tutorial
0Practical
3Total